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This book consists of nine chapters covering a variety of bioinformatics subjects, ranging from database resources for protein allergens, unravelling genetic determinants of complex disorders, characterization and prediction of regulatory motifs, computational methods for identifying the best classifiers and key disease genes in large-scale transcriptomic and proteomic experiments, functional characterization of inherently unfolded proteins/regions, protein interaction networks and flexible protein-protein docking. The computational algorithms are in general presented in a way that is accessible to advanced undergraduate students, graduate students and researchers in molecular biology and genetics. The book should also serve as stepping stones for mathematicians, biostatisticians, and computational scientists to cross their academic boundaries into the dynamic and ever-expanding field of bioinformatics.
Medical ethics. --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Moral and ethical aspects --- Medical bioinformatics
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Personal health and well-being was and is important for all individuals. This includes the way people are living, what they do to stay healthy as well as a profound, well-informed diagnosis and appropriate treatment in case of disease. To achieve these goals, modern medicine is provided with a large variety of tools to assess a patient's health state and collect the information required for a proper diagnosis and treatment, which is tailored to the patient's needs. Many of these available tools use signals either generated by the human body, for example, electroencephalogram (EEG) and electrocardiogram (ECG), or by interacting with the human body while traversing it like microwaves or reflected visible light that is recorded by a video camera. The biosignals recorded by the available and newly developed methods have to be processed to extract the information about the patient's condition and, analyzed tissue and cells. This book presents a small selection of the recent developments in the field of biosignal processing. The covered diagnostic tools and methods include the assessment of respiratory state through gait analysis, the contactless monitoring of cardiovascular and respiratory parameters using microwaves, a non-linear approach to extract the fetal ECG from non-invasive abdominal recordings, identification of epileptic networks from pre-surgical neurophysiological recordings and an improved method to obtain and validate the copy number alterations parameter, which are considered an important marker in cancer classification.
Medical ethics. --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Moral and ethical aspects --- Medical bioinformatics
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Medical Humanity and Inhumanity in the German-Speaking World is the first volume dedicated to exploring the interface of medicine, the human and the humane in the German-speaking lands. The volume tracks the designation and making through medicine of the human and inhuman, and the humane and inhumane, from the Middle Ages to the present day. Eight individual chapters undertake explorations into ways in which theories and practices of medicine in the German-speaking world have come to define the human, and highlight how such theories and practices have consolidated, or undermined, notions of humane behaviour. Cultural analysis is central to this investigation, foregrounding the reflection, refraction and indeed creation of these theories and practices in literature, life-writing and other discourses and media. Contributors bring to bear perspectives from literary studies, film studies, critical theory, cultural studies, history, and the history of medicine and psychiatry. Thus, this collection is historical in the most expansive sense, for it debates not only what historical accounts bring to our understanding of this topic. It encompasses too investigation of life-writing, documentary, and theory and literary works to bring to light elusive, paradoxical, underexplored - yet vital - issues in history and culture.
Medical ethics. --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Moral and ethical aspects
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Genomic variations and phenotypic diversity are closely linked and form the underlying mechanism for development of many human diseases. This book addresses the methods of detection, analysis, and interpretation of genomic variations in clinically relevant scenarios. If your research or clinical practice involves handling of genomic sequencing data, this book is for you. Topics covered include: methods for identifying genetic diversity, the workflow for analyzing whole exome and whole genome sequencing data, local ancestry deconvolution models, the value of molecular patterns and pattern biomarkers in cancer diagnosis and prognosis, and genotyping and profiling resistance-associated variants of hepatitis C. If your research or clinical practice involves handling of genomic sequencing data, this book is for you.
Medical ethics. --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Moral and ethical aspects --- Medical bioinformatics
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Independent Component Analysis (ICA) is a signal-processing method to extract independent sources given only observed data that are mixtures of the unknown sources. Recently, Blind Source Separation (BSS) by ICA has received considerable attention because of its potential signal-processing applications such as speech enhancement systems, image processing, telecommunications, medical signal processing and several data mining issues. This book brings the state-of-the-art of some of the most important current research of ICA related to Audio and Biomedical signal processing applications. The book is partly a textbook and partly a monograph. It is a textbook because it gives a detailed introduction to ICA applications. It is simultaneously a monograph because it presents several new results, concepts and further developments, which are brought together and published in the book.
Medical ethics. --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Moral and ethical aspects --- Medical bioinformatics
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With the changing composition of societies, there is growing consideration of questions of social diversity and equal access to healthcare for minority groups. Despite raised attention to this topic in recent years, there are still debates regarding implementation of healthcare equality in practice. Therefore, the aim of the contributions presented in this volume is a better understanding of the phenomenon of inequity and discrimination of minority groups in accessing healthcare from interdisciplinary perspectives of medical ethics, public health, and law. Such an understanding can lead to the determination of minorities' special needs concerning healthcare and barriers precluding them from benefitting from existing opportunities.
Bioethical Issues. --- Medical ethics. --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Moral and ethical aspects
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Dieses Open-Access-essential schafft Orientierung, wenn Künstliche Intelligenz im klinischen Alltag eingesetzt wird. Die Herausforderungen werden anhand zweier Beispiele aus dem Bereich der Nephrologie erläutert, die ethisch und rechtlich reflektiert werden. Ein umfangreicher Empfehlungsteil schließt diesen durchweg interdisziplinär erarbeiteten Band ab. Die Autor:innen Alle Autor:innen sind Teil des vom Bundesministerium für Bildung und Forschung geförderten Forschungsprojektes vALID Peter Dabrock ist seit 2010 Professor für Systematische Theologie II (Ethik) am Fachbereich Theologie der Friedrich-Alexander-Universität Erlangen-Nürnberg. Von 2016 bis 2020 war er Vorsitzender des Deutschen Ethikrates. David Samhammer ist Soziologe und Wissenschaftlicher Mitarbeiter am selben Lehrstuhl. Das Autorenteam umfasst weiterhin als Mediziner Klemens Budde und Bilgin Osmanodja aus der Medizinischen Klinik mit Schwerpunkt Nephrologie und internistische Intensivmedizin an der Charité - Universitätsmedizin Berlin und als Jurist:innen Susanne Beck, Simon Gerndt und Michelle Faber von der Leibniz Universität Hannover. Sebastian Möller leitet den Forschungsbereich "Speech and Language Technology" am Deutschen Forschungszentrum für Künstliche Intelligenz Berlin, dessen Mitglieder Aljoscha Burchardt und Roland Roller das Autorenteam abrunden.
Medical ethics. --- Nephrology. --- Nursing ethics. --- Nurses --- Nursing --- Professional ethics --- Medical ethics --- Internal medicine --- Kidneys --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Nursing ethics --- Social medicine --- Moral and ethical aspects --- Public health. --- Medical care. --- Medical Ethics. --- Technology --- Public Health. --- Health Care. --- Nursing Ethics. --- Ethics of Technology. --- Moral and ethical aspects. --- Technology and ethics --- Delivery of health care --- Delivery of medical care --- Health care --- Health care delivery --- Health services --- Healthcare --- Medical and health care industry --- Medical services --- Personal health services --- Public health --- Community health --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation
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Do the mechanisms of epigenetics control our genes? Or maybe not? The field of epigenetics investigates the complex molecular interaction of genes and their physical environment. Epigenetic mechanisms can alter our DNA structurally, change gene expression and thus drive cellular development throughout life. They have currently been associated with numerous diseases and are known to shape both appearance and behavioral patterns. Environmental factors as well as lifestyle choices come into play and impart their
Epigenetics. --- Medical ethics. --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Genetics --- Moral and ethical aspects --- Epigenomik --- DNA --- Grüne Gentechnologie --- Bioethik --- BBAW --- Pflanzen
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Obra que atende a estudantes e a profissionais da saúde não especialistas em bioética, mas interessados em conhecê-la, visto que normalmente se sentem profundamente incomodados com os problemas de sua prática habitual que apresentam interface com questões de natureza ética. Propõe-se a oferecer ao leitor um panorama da bioética em duas perspectivas: a da disciplina acadêmica e a do saber aplicado a diversos problemas relacionados ao cotidiano das práticas em saúde. E mais: busca expor a bioética como saber capaz de construir uma nova ponte entre a prática clínica e a prática em saúde pública. Se, por um lado, é difícil perseguir a originalidade quando se assume a tarefa de resumir um campo para leitores neófitos, por outro, esse é sempre um exercício à espera de ser feito, ainda mais em áreas tão interdisciplinares quanto é a bioética. Nesse sentido, o livro cumpre o prometido: de fácil leitura, convida à reflexão, ampliando as fronteiras do pensamento para quem tem o dever de exercitar a dúvida em situações como as provocadas pelo aborto, por exemplo, em que as crenças religiosas dos profissionais da saúde costumam se sobrepor aos deveres da assistência em saúde. Outro dado interessante: talvez por ser um campo tão aberto e com múltiplas fronteiras disciplinares, os autores deram preferência por não definir a bioética. Apresentaram-na por seu objeto de pesquisa e espaço de atuação, não por meio de conceitos. Para o público a que se dirige, essa pode ser uma estratégia eficaz, pois o aproximará pela experiência e não pela abstração da teoria.
Medical ethics. --- Bioethics. --- Biology --- Biomedical ethics --- Life sciences --- Life sciences ethics --- Science --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Moral and ethical aspects
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Traz um estudo da realidade da formação ética dos futuros médicos nas escolas de medicina do Brasil, retratando as dificuldades que os jovens profissionais se deparam quando deixam de ser formalmente aprendizes e passam a responder moral, jurídica e socialmente pela vida de um semelhante. Leitura necessária para os envolvidos com a formação moral do futuro médico.
Medical ethics. --- Teenagers --- Moral and ethical aspects. --- Adolescents --- Teen-agers --- Teens --- Young adults (Teenagers) --- Youth --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Moral and ethical aspects
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